Friday, March 20, 2009

JABSOM Researchers find New Use for Clofazimine

An old anti-leprosy drug might provide an effective treatment for three devastating autoimmune diseases -- multiple sclerosis, psoriasis and type 1 diabetes -- say two Hawaii researchers and mainland colleagues.

The finding is reported in the Public Library of Science by Drs. Reinhold Penner and Andrea Fleig of the University of Hawaii John A. Burns School of Medicine and the Queen's Medical Center, and researchers at Johns Hopkins University and Northwestern University.

Clofazimine Inhibits Human Kv1.3 Potassium Channel by Perturbing Calcium Oscillation in T Lymphocytes

Star Bulletin Article 2/23/2009

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