The Health Sciences Library, which opened in the Spring of 2005, serves as an information resource not only for the John A. Burns School of Medicine, but also for the University of Hawaii at Manoa campus, the UH system, and the State of Hawaii.
It is a normal protein. Everyone’s brain makes it. But the problem in Alzheimer’s is that it starts to accumulate into balls — plaques. The first sign the disease is developing — before there are any symptoms — is a buildup of amyloid. And for years, it seemed, the problem in Alzheimer’s was that brain cells were making too much of it.
But now, a surprising new study has found that that view appears to be wrong. It turns out that most people with Alzheimer’s seem to make perfectly normal amounts of amyloid. They just can’t get rid of it. It’s like an overflowing sink caused by a clogged drain instead of a faucet that does not turn off.
The National Institutes of Health has expanded a genetic and clinical research database to give researchers access to the first digital study images. The National Eye Institute (NEI), in collaboration with the National Center for Biotechnology Information (NCBI), has made available more than 72,000 lens photographs and fundus photographs of the back of the eye, collected from the participants of the Age-Related Eye Disease Study (AREDS).
These images are now accessible to scientists through NCBI's online database of Genotypes and Phenotypes, known as dbGaP, which archives data from studies that explore the relationship between genetic variations (genotype) and observable traits (phenotype). Though study descriptions and protocols are publicly accessible, researchers must apply for controlled access to de-identified information about study subjects, including the new images.
The Voyager Catalog "Get This Item" Services for book transfers and article requests will be turned off according to the schedule below. Requests will no longer be able to be placed online via Voyager from the listed dates until January 3, 2011.
Books from within the Health Sciences Library may still be checked out from the Library through December 17, 2010.
Voyager Services For
For books from other UH libraries except Hamilton and Sinclair Libraries
Friday, Dec. 3rd
Monday, Jan. 3rd
For books from Hamilton and Sinclair Libraries
Friday, Dec. 10th
Monday, Jan. 3rd
For articles from other UH libraries
Thursday, Dec. 16th (early a.m.)
Monday, Jan. 3rd
By any measure, the United States spends more on health care than any other nation. Yet according to the World Fact Book (published by the Central Intelligence Agency), it ranks 49th in life expectancy.
Researchers writing in the November issue of the journal, Health Affairs, say they know the answer. After citing statistical evidence showing that American patterns of obesity, smoking, traffic accidents and homicide are not the cause of lower life expectancy, they conclude that the problem is the health care system.http://www.nytimes.com/2010/11/30/health/30life.html?ref=health
News that annual CT lung scans can reduce the risk of lung cancer death among former and current heavy smokers was celebrated by national heath officials this month. A major government study found the screening scans saved the life of one person for every 300 current or former smokers who were scanned.But now cancer and screening experts are worried that the limited findings will be used by private screening centers to promote the test to a broader group than was studied. That, in turn, could lead to thousands of unnecessary lung scans, causing excess radiation exposure and unnecessary biopsies and surgery.
Public health officials hope that the new labels will re-energize the nation’s antismoking efforts, which have stalled in recent years. About 20.6 percent of the nation’s adults, or 46.6 million people, and about 19.5 percent of high school students, or 3.4 million teenagers, are smokers.
Every day, about 1,000 children and teenagers become regular smokers, and 4,000 try smoking for the first time. About 440,000 people die every year from smoking-related health problems, and the cost to treat such problems exceeds $96 billion a year.
There's still no vaccine for HIV, but researchers have made inroads in discovering new clues to why a minority of infected people can carry the virus without treatment.
Only about one in 300 people infected appear to have an immune system that can naturally suppress the virus's replication, and thus they carry low levels of the virus, the study said. Specific genetic variations may be responsible for this uncommon response to HIV, this study published in the journal Science found.http://pagingdrgupta.blogs.cnn.com/2010/11/05/new-clues-found-to-symptom-free-hiv/
In the three years since her son Diego was given a diagnosis of autism at age 2, Carmen Aguilar has made countless contributions to research on this perplexing disorder.
She has donated all manner of biological samples and agreed to keep journals of everything she’s eaten, inhaled or rubbed on her skin. Researchers attended the birth of her second son, Emilio, looking on as she pushed, leaving with Tupperware containers full of tissue samples, the placenta and the baby’s first stool.
Now the family is in yet another study, part of an effort by a network of scientists across North America to look for signs of autism as early as 6 months. (Now, the condition cannot be diagnosed reliably before age 2.) And here at the MIND Institute at the University of California Davis Medical Center, researchers are watching babies like Emilio in a pioneering effort to determine whether they can benefit from specific treatments.
Surgery is tough enough even when everything goes perfectly. But if the surgeon leaves something inside you, well, that's just plain bad.
Those leftovers can lead to infections, pain and other complications. Then there's the possibility of another operation to retrieve the stuff. Now, more operating rooms are being equipped with new gadgets to avoid misplaced equipment.
Some research indicates about 1 in around 1,000 patients undergoing abdominal surgeries wind up with an unintended souvenir. A push to improve quality has put mistakes like those on a list of "never events," errors that just shouldn't happen — ever.NPR Blogs October 6, 2010
Last week, University of Michigan Taubman Medical Library won the MLA Midwest Chapter's Jean Sayre Innovation Award for their Plain Language Medical Dictionary widget at http://www.lib.umich.edu/plain-language-dictionary.
It is based on CDC document, Plain Language Thesaurus for Health Communications, which I found online at http://depts.washington.edu/respcare/public/info/Plain_Language_Thesaurus_for_Health_Communications.pdf
More on how to use this widget is described in Patricia Andersen's blog at http://etechlib.wordpress.com/2010/09/17/plain-language-medical-dictionary-igoogle-gadgets-beyond-google/.
You can easily add to your iGoogle page.
Thanks to the University of Michigan and PF Anderson for this information.
An experimental brain cancer vaccine has been found to nearly double the life expectancy of some patients with the most aggressive form of the disease.
This study comes from research at Duke university medical center and M-D Anderson Cancer Center at the University of Texas. Karen Vaneman has one of the most aggressive forms of brain cancer -- a glioblastoma, which usually claims its victims within about 15 months after diagnosis.WebMD Brain Cancer Vaccine video
CDC Vital Signs offers recent data on the important health
topics of key diseases,conditions, or risk factors. Data is
gathered from CDC's national monitoring systems to show
progress in important areas of public health, and the ways
people can increase their health, prevent or control disease.
About 4 million to 5 million American children have persistent asthma, and about 90 percent of them also have allergies. Studies have found that treating the allergies can not only make asthmatic children more comfortable, but it can even keep them out of the emergency room.
"For the vast majority of children with asthma, allergies are a very important, if not the most important factor in causing symptoms and determining risk for hospitalizations and emergency room visits," says asthma expert Dr. William Busse of the University of Wisconsin.
Researchers are looking for adults 40-70 years old who have early signs of type 2 diabetes, but are not on any medication." And we're looking for people who are less than 250 pounds,” said Dr. Rodriguez. "We want men and women all races."
Patients who complete the study will receive $400.
Call #692-0908 for more information or visit http://www.yourhealthsite.org.
Created by Marc Hodosh and Richard Saul Wurman, TEDMED celebrates conversations that demonstrate the intersection and connections between all things medical and healthcare related: from personal health to public health, devices to design and Hollywood to the hospital. Together, this encompasses more than twenty percent of our GNP in America while touching everyone's life around the globe.
The first, by Claus Yding Andersen, MD, of the University of Copenhagen, and colleagues, found significant reductions in germ and somatic cells in the testes of male embryos from mothers who smoked during pregnancy, possibly related to the polycyclic aromatic hydrocarbons found in cigarette smoke.
"This effect may have long-term consequences on the future fertility of exposed offspring," the authors wrote online in Human Reproduction.http://www.medpagetoday.com/PrimaryCare/Smoking/22069
The National Institutes of Health issued a notice late Monday on the federal district court injunction blocking the federal funding of human embryonic stem cell research. The notice confirms the information provided by Dr. Francis Collins last week in a call with the media. The notice states that grant awards that were funded on or before August 23, 2010, are not affected by the preliminary injunction order, and award recipients may continue to expend the funds awarded to them prior to the date of the injunction. However, pending competing and noncompeting continuation hESC awards and contracts are suspended until further notice, and the peer review of all pending competing hESC applications and proposals also are suspended.
NIH has ordered the termination of all NIH intramural human embryonic stem cell research. Deputy Director Dr. Michael Gottesman wrote in an email to intramural scientists, "HHS has determined that the recent preliminary injunction ordered by the United States District Court for the District of Columbia in the matter of Sherley v. Sebelius is applicable to the use of human embryonic stem cells (hESCs) in intramural research projects. In light of this determination, effective today August 27, 2010, all intramural scientists who use hESC lines should initiate procedures to terminate these projects. Procedures that will conserve and protect the research resources should be followed."
The new issue of The New Yorker features an article on Dr. Francis Collins, director of the NIH, and the recent injunction barring federal funding of human embryonic stem cell research. A new supplement released Monday to the September issue of Academic Medicine highlights the innovations in medical education curriculum since 2000. “A Snapshot of Medical Student Education in the United States and Canada” coincides with the centennial anniversary of the landmark Flexner report and examines advances in medical education curriculum at 128 U.S. and Canadian medical schools. In addition to the school reports, articles on the history and future of medical education and how the health care system has affected the development of the medical education system are included from authors such as Lois M. Nora, M.D., J.D., M.B.A., Brian David Hodges, M.D., Ph.D., Barbara Barzansky, Ph.D., Susan E. Skochelak, M.D., M.P.H., and Donald M. Berwick, M.D., M.P.P. An article distributed by Bloomberg on Tuesday discussed the impact stimulus funding has had on research and how the ending of such funding is causing some pain. An editorial in Monday's Chicago Sun Times highlights the University of Chicago's Urban Health Initiative. The editorial states, "...we see some reason to believe the project is making successful inroads in redirecting a significant number of people away from the ER and toward the clinics and community hospitals. If those numbers grow, and if the quality of care at the referral sites is demonstrably high, this project could serve as a model for similar efforts across the nation. We sincerely hope so. Bold efforts such as this are essential if the United States is to get a grip on the spiraling cost of health care." The Wall Street Journal on Monday featured an article titled, "Cash-Poor Governments Ditching Public Hospitals." The article reports, "More than a fifth of the nation's 5,000 hospitals are owned by governments and many are drowning in debt caused by rising health-care costs, a spike in uninsured patients, cuts in Medicare and Medicaid and payments on construction bonds sold in fatter times. Because most public hospitals tend to be solo operations, they don't enjoy the economies of scale, or more generous insurance contracts, which bolster revenue at many larger nonprofit and for-profit systems.Local officials also predict an expensive future as new requirements—for technology, quality accounting and care coordination—start under the overhaul, which became law in March."
The new issue of The New Yorker features an article on Dr. Francis Collins, director of the NIH, and the recent injunction barring federal funding of human embryonic stem cell research.
A new supplement released Monday to the September issue of Academic Medicine highlights the innovations in medical education curriculum since 2000. “A Snapshot of Medical Student Education in the United States and Canada” coincides with the centennial anniversary of the landmark Flexner report and examines advances in medical education curriculum at 128 U.S. and Canadian medical schools. In addition to the school reports, articles on the history and future of medical education and how the health care system has affected the development of the medical education system are included from authors such as Lois M. Nora, M.D., J.D., M.B.A., Brian David Hodges, M.D., Ph.D., Barbara Barzansky, Ph.D., Susan E. Skochelak, M.D., M.P.H., and Donald M. Berwick, M.D., M.P.P.
An article distributed by Bloomberg on Tuesday discussed the impact stimulus funding has had on research and how the ending of such funding is causing some pain.
An editorial in Monday's Chicago Sun Times highlights the University of Chicago's Urban Health Initiative. The editorial states, "...we see some reason to believe the project is making successful inroads in redirecting a significant number of people away from the ER and toward the clinics and community hospitals. If those numbers grow, and if the quality of care at the referral sites is demonstrably high, this project could serve as a model for similar efforts across the nation. We sincerely hope so. Bold efforts such as this are essential if the United States is to get a grip on the spiraling cost of health care."
The Wall Street Journal on Monday featured an article titled, "Cash-Poor Governments Ditching Public Hospitals." The article reports, "More than a fifth of the nation's 5,000 hospitals are owned by governments and many are drowning in debt caused by rising health-care costs, a spike in uninsured patients, cuts in Medicare and Medicaid and payments on construction bonds sold in fatter times. Because most public hospitals tend to be solo operations, they don't enjoy the economies of scale, or more generous insurance contracts, which bolster revenue at many larger nonprofit and for-profit systems.Local officials also predict an expensive future as new requirements—for technology, quality accounting and care coordination—start under the overhaul, which became law in March."
Mind if movie stars smoke? Actually, quite a few people do.
Foes of smoking say that when larger-than-life celebrities light up on the big screen, it raises the odds that young people will take up the bad health habit.
An advocacy group audited the cameo roles of tobacco in the top-grossing movies going back to 1991 and found the number of smoking scenes has fallen in recent years. But they're still pretty common.
After peaking in 2005, on-screen smoking in the top movies has declined by almost half to 1,935 recorded instances in 2009. All told, 51 percent of the top movies in 2009 didn't show tobacco use at all, the first time a majority, albeit a thin one, of big films have been tobacco-free.
For movies kids are most likely to see (rated G, PG and PG-13), 61 percent were tobacco-free last year.
The findings appear in the latest issue of Morbidity and Mortality Weekly Report, where you can find lots more details on how the movie watchers cataloged smoking incidents.
You might recall that back in 1998, tobacco companies agreed to stop paying to have their cigarettes placed in movies and such. Since then, antismoking groups have been ratcheting up the pressure on movie makers to eliminate the depiction of smoking in their films.
According to an article published in Archives of Internal Medicine, eating more white rice raised the risk for type 2 diabetes in a large clinical study, whereas eating more brown rice reduced the risk.
Type 2 diabetes is one of the fastest growing health problems in Americans of all ages. Being overweight or inactive increases your chances of developing the disease. Research suggests that eating more refined foods, including white bread and sugary foods, might also raise the risk.
The new study followed about 200,000 people for up to 22 years. The people who ate at least 5 weekly servings of white rice had a 17% higher risk than those who ate less than 1 serving per month.
On the other hand, people who ate at least 2 servings of brown rice a week had an 11% lower risk of developing type 2 diabetes than those who ate less than 1 serving a month."We believe replacing white rice and other refined grains with whole grains, including brown rice, would help lower the risk of type 2 diabetes," says study co-author Dr. Qi Sun of Brigham and Women’s Hospital in Boston.
Less than 10 percent of U.S. adults limit their daily sodium intake to recommended levels, according to a new report, "Sodium Intake in Adults – United States, 2005-2006," published today in CDC's Morbidity and Mortality Weekly Report. The report also finds that most sodium in the American diet comes from processed grains such as pizza and cookies, and meats, including poultry and luncheon meats.
According to the report, U.S. adults consume an average of 3,466 milligrams (mg) of sodium per day, more than twice the current recommended limit for most Americans. Grains provide 36.9 percent of this total, followed by dishes containing meat, poultry, and fish (27.9 percent). These two categories combined account for almost two-thirds of the daily sodium intake for Americans.
+ Author Affiliations
Background: The basic purpose of medical schools is to educate physicians to care for the national population. Fulfilling this goal requires an adequate number of primary care physicians, adequate distribution of physicians to underserved areas, and a sufficient number of minority physicians in the workforce.
Objective: To develop a metric called the social mission score to evaluate medical school output in these 3 dimensions.
Design: Secondary analysis of data from the American Medical Association (AMA) Physician Masterfile and of data on race and ethnicity in medical schools from the Association of American Medical Colleges and the Association of American Colleges of Osteopathic Medicine.
Setting: U.S. medical schools.
Participants: 60 043 physicians in active practice who graduated from medical school between 1999 and 2001.
Measurements: The percentage of graduates who practice primary care, work in health professional shortage areas, and are underrepresented minorities, combined into a composite social mission score.
Results: The contribution of medical schools to the social mission of medical education varied substantially. Three historically black colleges had the highest social mission rankings. Public and community-based medical schools had higher social mission scores than private and non–community-based schools. National Institutes of Health funding was inversely associated with social mission scores. Medical schools in the northeastern United States and in more urban areas were less likely to produce primary care physicians and physicians who practice in underserved areas.
Limitations: The AMA Physician Masterfile has limitations, including specialty self-designation by physicians, inconsistencies in reporting work addresses, and delays in information updates. The public good provided by medical schools may include contributions not reflected in the social mission score. The study was not designed to evaluate quality of care provided by medical school graduates.
Conclusion: Medical schools vary substantially in their contribution to the social mission of medical education. School rankings based on the social mission score differ from those that use research funding and subjective assessments of school reputation. These findings suggest that initiatives at the medical school level could increase the proportion of physicians who practice primary care, work in underserved areas, and are underrepresented minorities.
Primary Funding Source: Josiah Macy, Jr. Foundation.
Grant Support: By the Josiah Macy, Jr. Foundation.
Potential Conflicts of Interest: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M09-2257.
The National Library of Medicine® (NLM) Health Hotlines is now available as an app for the iPhone® and iPod Touch®. Health Hotlines is also compatible with the iPad®.
Health Hotlines is a compilation of organizations with toll-free telephone numbers which can assist the public in locating health-related information. It is derived from DIRLINE®, the NLM Directory of Information Resources Online. DIRLINE contains descriptions of almost 9,000 health and biomedical organizations and resources. Some subject areas included in Health Hotlines include AIDS, cancer, diseases and disorders, maternal and child health, aging, substance abuse, disabilities and mental health.
NIH Public Access Policy Citation Management Tool
Beginning July 23, 2010, program directors and principal investigators must use My NCBI’s “My Bibliography” tool to manage their professional bibliographies. They will no longer be able to enter citations manually into eRA Commons.
To ease investigators’ bibliography management, improve data quality, and ensure compliance with the National Institutes of Health (NIH) public access policy, eRA Commons has linked to the National Center for Biotechnology Information’s (NCBI’s) personal online tool, “My NCBI.” Using “My Bibliography,” users can maintain and manage a list of all types of their authored works, such as articles, presentations, and books.
When a new or existing My NCBI account is linked to a Commons account, citations added to My Bibliography will appear automatically in the Commons account. Investigators and their delegates will benefit from My Bibliography’s ability to query the National Library of Medicine’s PubMed and PubMed Central databases, as well as the NIH Manuscript Submission system, and import citation data directly from those sources. Users can access My NCBI from Commons, or they can log in directly to My NCBI using their Commons username and password.
For more information on how investigators should handle the upcoming changes, see notice number NOT-OD-10-103. Read the step-by-step guide for how to set up a “My NCBI” account and access “My Bibliography.”
UH System Current News
Faculty Members (Clinical Faculty and Full-time Faculty)
at the John A. Burns School of Medicine, University
of Hawai'i at Mānoa.
There are many questions people have about seasonal and the 2009 H1N1 flu. CDC has developed several broadcast quality videos that focus on some of the different topics for which the public is seeking information such as warning signs of the flu, preventing its spread and taking antiviral medications.
Four "Influenza Roundtable" videos were filmed, featuring Dr. Joe Bresee, Chief of the Epidemiology and Prevention Branch in CDC's Influenza Division. These videos provide easy to understand answers for the public and provide important public health recommendations and action steps to protect their health and the health of their families.http://www.cdc.gov/news/2009/11/flu_roundtable/
NLM recently announced two newly-issued grant programs, NLM Information Resource Grants to Reduce Health Disparities and NLM Independent Career Development Award for Biomedical Informatics. Applications for both programs must be submitted through Grants.gov.
The grant program to reduce health disparities solicits applications for projects that will bring useful, usable health information to populations affected by health disparities and the health care providers who care for them. Proposed projects should utilize the capabilities of computer and information technology and health sciences libraries to bring health-related information to consumers and their health care providers. The application deadline is July 14, 2010.
The purpose of the NLM Independent Career Development Award for Biomedical Informatics program is to facilitate the transition of investigators from the mentored to the independent stage of their careers. The award applies to research in clinical informatics, public health informatics or translational informatics. Preference will be given to candidates who received their informatics training at one of NLM’s university-based training programs in biomedical informatics. There are multiple application deadline dates.
Additional information regarding both grant programs is available in this recently published Latitudes article, http://nnlm.gov/psr/newsletter/?p=2883.
Thanks to Alan Carr at UCLA